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Managing Your Menopause Type® Educational
Class |
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Session Three - Your Risks of Disease |
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INSULIN RESISTANCE & DIABETES |
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The Relationship Between Menopause And Abnormal
Blood Sugar Metabolism |
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The relationship between menopause and abnormal
blood sugar metabolism was presented on pages 73 through 76 of "What's
Your Menopause Type?", presented in this excerpt from the book. |
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Blood Sugar and
Insulin Problems |
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Blood sugar problems can arise with various
menopause types, due to imbalances in all three of the steroid hormones we
have been looking at: estrogen, progesterone, and testosterone. These are
some of the most serious health risks of menopause. |
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Insulin is a hormone that
enables your cells to use molecules of sugar (glucose) from your blood.
Glucose is the main source of energy for most of your body's cells. To
receive molecules of glucose, your cells must be sensitive to the influence
of insulin |
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For various reasons, your cells
can become "insulin resistant" or less sensitive. Your body still
provides the same amount of insulin, but your cells seem to need more. When
this happens, your body tries to compensate by making more insulin. This
leads to a condition called hyperinsulinemia, literally meaning "too
much insulin in the blood." |
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Hyperinsulinemia with insulin
resistance is responsible for a range of serious illnesses in postmenopausal
women, including adult-onset diabetes, heart disease, and cancer of the
breast and uterus.122-129 |
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It was once thought that insulin
resistance was mainly a problem of obesity, but this isn't true. Insulin
resistance is a widespread but largely unrecognized threat to women's health.
As many as 44% of healthy postmenopausal women may have insulin resistance |
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Insulin Resistance is a widespread but largely
unrecognized threat to women's health. |
What causes insulin resistance? Imbalances in
estrogen, progesterone, and testosterone levels in women make insulin
resistance more likely in each year after menopause. |
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A deficiency in estrogen can
produce insulin resistance. 132-134 Estrogen plays an important role in your body's normal insulin
sensitivity, the uptake of glucose by muscle cells, the normalization of
proteins that carry hormones in the blood (which help normalize testosterone
levels), and the liver's ability to clear excess insulin from the blood. 135-139 |
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Progesterone has the opposite
effect: It can cause insulin resistance. 140-142 The elevated
progesterone seen in pregnancy has been suspected to contribute to the
formation of gestational diabetes. 143-145 Supplemental
progesterone used in hormone-replacement therapy has also been found to
interfere with insulin and glucose metabolism. 146-151 (See
chapter 14 for morn information on hormone-replacement therapy.) |
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Later in this chapter, I explain
the importance of the progesterone-to-estrogen ratio. If the level of
estrogen is too low to balance progesterone, even a normal level of
progesterone can promote insulin resistance. This may occur with low-estrogen
and normal-progesterone menopause types® . |
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A high testosterone level can
also cause insulin resistance and hyperinsulinemia, especially when it is not
balanced by estrogen. 152-157 This is true for premenopausal women, as well as women who are
in or past menopause. 158 |
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Thus, any menopause type®
that includes low levels of estrogen or high levels of testosterone has an
increased risk for insulin resistance--especially if there is an imbalance
between estrogen and progesterone, or estrogen and testosterone. Since
insulin resistance can contribute to so many serious health risks, from
diabetes to heart disease and cancer, this is one of the strongest reasons
for identifying your menopause type® and getting appropriate
treatment. |
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"What's Your Menopause Type?", pg 73-76 |
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What's
Next? |
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Next
we will address the questions "Are hormones the answer?",
"What about weight?" & "How does weight affect insulin
resistance?" |
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We
will then discuss the need to see the big picture if we are going to stop the
progression of insulin resistance and diabetes |
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The Managing Your Menopause Type® Educational Class
is provided to the public without charge. This information is provide for
education purposes only, and is not intended to prescribe treatment. Consult
a physician, pharmacist or other healthcare professional regarding the
applicability of any opinions or recommendations with respect to your
symptoms or medical condition. |
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